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They may include increased GSH utilization upon exposure to oxygen, insufficient GSH synthesis due to immature synthesis enzymes or to reduced availability of cysteine, the rate-limiting precursor amino acid for GSH synthesis, or impaired regeneration of oxidized glutathione (GSSG) to GSH

Furthermore, mature oligodendrocytes are capable of facilitating remyelination after damage in cats and non-human primates, while maintaining established myelin sheaths (Duncan et al., 2018)

This review presents a birds eye overview of some of the current topics of controversy and/or areas where knowledge is currently lacking

It is characterized by a high propensity for metastasis and an exceptionally malignant clinical course