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The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling

J Affect Disord (2013) 150:72735.10.1016/j.jad.2013.05.083 95 BlumbergHPKrystalJHBansalRMartinADziuraJDurkinKet alAge, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study

Therefore, a true overdose that causes toxicity is extremely rare

One of these mechanisms is through the activation of transcription factors, such as nuclear factor erythroid 2 (NRF2), which promotes the expression of genes involved in oxidative stress response