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Van Haren RM, Rajaram R, Correa AM, Mehran RJ, Antonoff MB, Hofstetter WL, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Rice DC , Roth JA

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Unmasking transcriptional heterogeneity in senescent cells

confirmed that alcohol intake upregulates miR-155 to reduce the protein expression of Lysosomal-associated membrane protein 1 and 2 (LAMP1 and LAMP2) in the liver, leading to impaired autophagy function of lysosomes and reduced autophagy flux (Lu et al., 2023a)