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The lower intracellular levels of serine and glycine in cancer cells that we observed in vitro indicate a high turnover with increased consumption and usage of these amino acids in downstream biosynthetic pathways, which is supported by the enhanced SHMT2 expression in response to RT

Glutathione supports this process by protecting the mitochondria, which are the "powerhouses" of your cells where energy is produced

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Oncogene 22 , 24432451 (2003)