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Antidrug antibodies in psoriasis: a systematic review

These limitations severely restrict their therapeutic application

Specifically, L2-Cmu was engineered as a human/murine chimera (i.e., reverse chimeric antibody), such that the complementary-determining regions (CDRs) were engineered into a new framework in which the entirety of the variable regions are human and the constant regions are mouse

Make sure that the solution is clear and discard it if there are any visible particles or cloudiness Also, make sure to get a puncture-resistant container as well in order to dispose of your needles and syringes safely