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Delivery luteolin with folacin-modified nanoparticle for glioma therapy

ER stress can also be caused by other mechanisms such as inhibition of ERG transport, which results in accumulation of secretory proteins within the ER (Hyer-Hansen and Jttel, As it is known, mutations of SOD1 in transgenic rats or mice induced motor neuron disease (Gurney, G93A causes protein aggregation inducing cellular damage (Bendotti and Carr, SOD1 as neuromodulator Many studies pointed out that muscarinic receptors are widely expressed in the central nervous system controlling several neuronal functions