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Our comprehensive analysis of the RNA genomes of two cytoplasmic-replicating viruses, CHIKV and DENV, found no evidence of m 6 A modifications in their genomes, despite previous reports indicating their presence 39,41

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In fact, TDP-43 interacts with several proteins involved in the mRNA splicing and other RNA metabolisms in the nucleus, and also interacts with several cytoplasmic proteins, such as those involved in the mRNA translation (Freibaum et al., 2010

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