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B12 injections are also used to treat people with malabsorption (gastrointestinal conditions that prevent proper absorption of B12 from the gut), for example, people with atrophic gastritis (stomach inflammation) and intrinsic factor deficiency (pernicious anemia) or those who have undergone surgical procedures such as gastrectomy or small bowel resection (stomach or intestine removed), autoimmune diseases, etc

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The duration of the benefits can vary depending on the individuals lifestyle and the type of vitamin injected but typically last for several days to weeks

A 2021 systematic review concluded that there was significant evidence for using B12 as part of a treatment plan for neuropathic pain