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The viral hijack of human ACE2 receptor disrupts RAAS activation, upregulates NF-B pathway, triggers cytokine storm, hypertension, cell proliferation, inflammation, and fibrosis, where all elicit detrimental effects on every bodily organ during SARS-CoV-2 infection 635

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Reported injuries associated with intramuscular injection sites used for intramuscular injections include: Permanent damage to radial and axially nerves resulting in paralysis/ neuropathy Persistent nodules gramulomas, muscle contractures and/or palsy Peripheral nerve and bone injury Local irritation, pain local discomfort and redness at the site Infection, abscess, cellulitis and tissue necrosis Haematomas, bleeding, arterial punctures and, in rare cases, gangrene Muscle fibrosis