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When measuring cardiovascular effects, a low but statically significant increase in heart rate was noted but no significant effect on blood pressure at any of the doses tested

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Taken together, these findings indicate that mitochondrial ROS in EMs is not a nonspecific byproduct, but a coordinated, iron-amplified, and respiration-driven signal of metabolic stress that contributes to lesion persistence, inflammation, and tissue remodeling

Furthermore, difficult digestion (postprandial heaviness, discomfort, bloating) can reflect a lack of fiber, a diet too rich in ultra-processed foods, poor tolerance to certain foods, or an unsuitable meal rhythm