glutathione leve Reduced (GSH) and total glutathione levels in hPCLS Causes of Low Glutathione Levels

GSH is predominantly in its thiol-reduced form inside the cells, except in the lumen of the endoplasmic reticulum where it exists only in its GSSG form (Figures 2, 4)

Similarly, coronary artery disease patients with single, double, or triple-vessel stenosis and patients with acute coronary syndrome had a significant increase in malondialdehyde levels and the percentage of malondialdehyde release, associated with a marked decrease in GSH concentration, total antioxidant capacity and erythrocyte GSH peroxidase activity compared with controls (154)

Next, samples were centrifuged at 17,000 g for 10 min and 800 l supernatant was dried in a vacuum evaporator (Thermo)

G., Faulkner, R., Mirsky, A