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In some contexts, FPR2 deficiency reduces macrophage infiltration and attenuates lesion development, whereas in others, it lowers collagen content and increases plaque instability [130]

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4-HNE in high concentrations is one of the most toxic and mutagenic metabolites of lipid peroxidation for the cell (Nicolaou et al., 2010

Relevant to laboratory investigations involving pineal peptide biology, CNS signaling, neuroprotective pathway models, and peptide-fragment response systems