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doi: 10.1038/s41375-022-01613-1 3 HochmanMJDeZernAE

doi: 10.1096/fj.01-0278fje

From a mechanistic perspective, evidence shows that NMN treatment upregulates SIRT1 expression, regulates the MSCs in aging bone marrow through the SIRT1 pathway, and thus promotes bone formation and reduces adipogenesis [49]

Serum heart-type fatty acid-binding protein (H-FABP) levels were measured by ELISA, and reactive oxygen species (ROS) levels were determined by flow cytometry