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Instead of being a signal of meal initiation, this increase can instigate processes in the CNS which prepare the body to receive and process incoming nutrients appropriately

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A significant body of work, often based on neuroimaging techniques such as positron emission tomography (PET) and blood-oxygen-level-dependent functional magnetic resonance imaging (BOLD-fMRI), has reported a disproportionate increase in glucose utilization relative to oxygen consumption during brain activation

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