glutathione deficiency peripheral neuropathy Diabetic Neuropathy: Current Epidemiology, Diagnostic Advances, Biomarkers, and Management Strategies Glutathione: Lights and Shadows in

Its protective mechanism may involve the activation of the Nrf2/ARE and PI3K/Akt pathways, thereby reducing inflammation, oxidative stress, and apoptosis, which helps mitigate the progression of diabetic cardiomyopathy

Besides, suckling piglets in the CAT group had higher plasma concentrations of C22:0 ceramides than in the CON group, which was a favorable phenomenon because of the pleiotropic effects of ceramides such as regulating apoptosis, differentiation, proliferation, and stress responses (32)

Currently, the natural compounds for ferroptosis in lung cancer mainly include terpenoids, alkaloids, phenols, quinones and saponins, and also contain few steroids and flavonoids

243-245 An observational study that included data from 359 subjects with fibromyalgia found inclusion of PEA in therapy was associated with reduced pain and improved quality of life scores