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ICP-MS analysis revealed extremely low residual levels of the element Ru in the major organs of rats in the Ru SA+AC group (Fig

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Unlike classical inflammation (characterized by heat, redness, and pain), neuroinflammation primarily involves the release of pro-inflammatory mediators (e.g., cytokines, chemokines, and ROS) by resident immune cells, particularly microglia, the CNSs innate immune effectors [110, 111]

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