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Clark, C

Shadzi MR, Rahmanian M, Heydari A, Salehi A

Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes

Several clinical trials of HCQ in combination with cytotoxic (docetaxel, temozolomide) and targeted (an HDAC inhibitor, a vascular endothelial growth factor receptor [VEGFR] inhibitor, gefitinib) agents are underway, based on the premise that inhibition of autophagy by HCQ should enhance the efficacy of these drugs