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Oct 2015;25(10):779-84 e1

JKE-1674 can convert into a nitrile oxide JKE-1777

Acting as enzyme cofactors, they mediate hydrogen atom transfer in catabolic redox reactions ( + can be phosphorylated to nicotinamide adenine dinucleotide phosphate (NADP + ) under the catalysis of nicotinamide adenine dinucleotide kinase (NADK)

(iv) the 2-oxoadipate dehydrogenase complex that catalyzes the decarboxylation of 2-oxoadipate to glutaryl-CoA in the catabolic pathway of lysine, hydroxylysine, and tryptophan