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[38 ]It is clear from these data that the effects of the retinoids as sole therapeutic agents are limited, perhaps mainly to hematologic malignancies, which tend to develop RA resistance over time

Disclosures: Hongqin Xu: Nothing to Disclose, Yanhang Gao: Nothing to Disclose 1033 SALIVARY MICROBIOME IS INDEPENDENTLY ASSOCIATED WITH HOSPITALIZATIONS IN A MULTI-CENTER PROSPECTIVE COHORT OF OUTPATIENTS WITH CIRRHOSIS: NACSELD3 EXPERIENCE Jasmohan Bajaj 1 Masoumeh Sikaroodi 2 Marcela Pea Rodrguez 3 Puneeta Tandon 4 Jennifer Lai 5 Jacqueline Oleary 6 Guadalupe Garcia-Tsao 7 Florence Wong 8 Hugo Vargas 9 Scott Biggins 10 Patrick Kamath 11 Brian Bush 12 K Rajender Reddy 13 Patrick Gillevet 2 , 1 Virginia Commonwealth University, 2 George Mason University, 3 Universidad de Guadalajara, 4 University of Alberta, 5 UCSF, 6 Dallas VAMC, 7 Yale University, 8 University of Toronto, 9 Mayo Clinic Arizona, 10 UPMC, 11 Mayo Clinic Rochester, 12 VCU, 13 University of Pennsylvania Background: Inflammation is a main driver of poor outcomes in cirrhosis

This value was then subtracted from the intensity measurement generated from neuronal areas of interest

Ferroptosis may also lead to normal tissue damage caused by radiation therapy (10)