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How PlexusDx Supports a More Personalized Approach PlexusDx's Precision Peptide Genetic Test reveals predispositions in metabolic and antioxidant pathways, including variants affecting glutathione synthesis (GCLC), oxidative stress resilience (SOD2, CAT), and thyroid autoimmunity (HLA, CTLA4)

GPX4 uses reduced GSH to reduce toxic lipid peroxides (such as phosphatidylethanolamine hydroperoxide, PE-OOH) to non-toxic lipid alcohols through the selenocysteine residue in its active center, thereby maintaining cell membrane stability and blocking the ferroptosis process (150, 151)

Pandian, N

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