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Inclusion criteria were any treatment report of GSH for skin lightening (or hyperpigmentation) and GSH for any randomised control trial (RCT) for the first and second searches, respectively

Furthermore, in the maternal immune activation (MIA) mouse model induced by poly(I:C), low-dose clonazepam treatment increased inhibitory neurotransmission and reduced neural activity in the prefrontal cortex of offspring, which helped prevent social deficits, anxiety, and depression-like behaviors (142)

No single cream, peel, or laser clears it permanently because the condition has multiple drivers: ultraviolet and visible light exposure, hormones, inflammation, genetics, and blood vessel activity in the skin

Plant Cell 18:32353251 Maruyama-Nakashita A, Watanabe-Takahashi A, Inoue E, Yamaya T, Saito K, Takahashi H (2015) Sulfurresponsive elements in the 3'-nontranscribed intergenic region are essential for the induction of SULFATE TRANSPORTER 2;1 gene expression in Arabidopsis roots under sulfur deficiency