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The hypoxic microenvironment of RA joints can cause reactive oxygen species (ROS) accumulation and mitochondrial damage, which not only affect the metabolic processes of immune cells and pathological changes in fibroblastic synovial cells but also upregulate the expression of several inflammatory pathways, ultimately promoting inflammation

L-Carnitin hat antioxidative Schutzwirkung Studien haben belegt, dass eine L-Carnitin-Supplementierung bei Sportlerinnen und Sportlern nach krperlicher Belastung zu tieferen Laktat-, Cortisol-, Creatinkinase- und Ammoniak-Werten fhrt, was geringeren oxidativen Stress bedeutet (4, 5, 6)

EMT results in the loss of epithelial cell polarity and cell-cell junctions, transforming them into migratory mesenchymal cells[11, 12]

Autophagy 8 , 144146 (2012)