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It can quickly and effectively restore disordered colonic activity and significantly ameliorate GI function, so it may be beneficial to the treatment of constipation (West et al., 2020)

To explore this notion, we installed the BDHI electrophile onto a set of chemical fragments (so called scout fragments) previously shown to drive covalent protein engagement with different electronic and steric properties 2 and assessed their proteomic reactivity

We found that Gpx1 expression and activity increased in the liver of mice with Con A administration

doi: 10.1186/s13287-019-1307-9 80 Kornicka-GarbowskaKGroborzSLyndaBGaluppoLMaryczK