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Intranasal administration achieved median Tmax of 0.50 hours with terminal half-life ranging from 1.85 to 2.09 hours in male studies

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10.1136/thorax.2003.005611

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Here the Intrinsic Factor binds to the B12 and the "B12/IF Complex" enters the cells on the wall of the Ileum after binding to receptors on the surface of the Ileal cells, allowing it to enter the blood stream

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