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Women taking long-term medications such as metformin (for diabetes or polycystic ovary syndrome) or proton pump inhibitors (for acid reflux) may also have reduced B12 absorption

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In recent years, regular administration of probiotics, such as Bifidobacterium and Lactobacillus , has also been considered a potential method for preventing IBD (Manzoor et al., 2022), which further indicates the importance of the intestinal flora in IBD (Figure 2

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