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It is naturally found in high concentrations in the liver, and plays a critical role in detoxification processes there by binding to toxins and facilitating their removal from the body

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It comes from a larger hormone system tied to immune calming in the body

PMID: 36873174 Adv Sci (Weinh) Targeting the SOX9/TIMP1 Axis with iRGD-Conjugated Nanoplatform Enhances Dendritic Cell Function and Photodynamic Immunotherapy in Gastric Cancer