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In order to test a possible effect of intracellular glutathione synthesis in such a process, buthionine sulfoximine (BSO), a specific the inhibitor of gamma-glutamylcysteine synthetase, was used to block the first step of intracellular glutathione synthesis

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In its May 2026 evaluation, the FDA identified one small meeting abstract describing a short randomized study in people with ulcerative colitis