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Description

Treatment with either NR or the PARP inhibitor Olaparib resulted in improvements at the mitochondrial and proteostasis level

In 2023, an international panel of experts reached a consensus and the European Association for the Study of the Liver, from an etiological perspective, renamed it as 'metabolic dysfunction-associated steatotic liver disease (MASLD)' (6,7)

An imbalance between free radical production and the bodys antioxidant defenses leads to oxidative stress, which is implicated in the pathogenesis of numerous diseases (Table 2) [8]