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Importantly, these effects occur without activation of growth hormone receptor pathways or alteration of IGF-1 signaling, allowing AOD 9604 to be used as a tool for isolating metabolic signaling mechanisms

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Deficiency is common in those with fatigue, brain fog, or nutrient absorption issues, especially individuals with gastrointestinal conditions, vegans and vegetarians, or those taking medications like metformin or proton-pump inhibitors