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Storage requirements Lyophilized powder (before reconstitution): Store frozen at -20C (-4F) for long-term storage Stable at refrigerator temperature (2-8C) for several months Avoid freeze-thaw cycles Reconstituted solution or nasal spray: Refrigerate at 2-8C (35-46F) Protect from light Do not freeze reconstituted solution Shelf life: approximately 28 days after reconstitution Commercial nasal sprays: Follow manufacturer instructions Most require refrigeration after opening Typical shelf life: 30-60 days after opening Signs of degradation Cloudiness or particulate matter Color change Reduced effectiveness Unusual odor If any of these occur, discard the product