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Abbreviations ALT: Alanine aminotransferase AST: Aspartate transaminase BVDV: Bovine viral diarrhea virus CD14: Cluster of differentiation 14 Cp: Ceruloplasmin CPK: Creatine phosphokinase CRP: C-reactive protein cTnI: Cardiac troponin I GAPDH: Glyceraldehyde-3-phosphate dehydrogenase GGT: Gamma-glutamyl transferase GPX: Glutathione peroxidase Hp: Haptoglobin IRF3: Interferon regulatory factor 3 LDH: Lactic dehydrogenase PRDX2: Peroxiredoxin 2 PRDX6: Peroxiredoxin 6 PTX3: Pentraxin 3 SAA: Serum amyloid A SLC11A1: Solute carrier family 11 member 1 ST1P1: Stress-induced phosphoprotein 1 References Faid-allah, E

In high-altitude cerebral edema (HACE) which is characterized by inflammation and hypoxia, proteins in the nucleosome remodeling and histone deacetylase (NuRD) complex of microglial is lactylated, which upregulates the expression of various pro-inflammatory factors in M1-type microglia and enhances NF-B pathway activity, thereby exacerbating LPS-induced neuroinflammatory conditions [133]

Another paper in Ageing Research Reviews found that NAD may replenish NAD levels in aged tissues and exhibit beneficial effects against aging and aging-related diseases