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Lower NAD levels have been linked to age-related changes, including: Researchers continue to study how NAD levels may affect aging

Surgery and Other Treatments Oxygen therapy

doi: 10.1007/s00540-013-1741-2 98 SuQLiuYLvXWYeZLSunYHKongBHet al

However, in COPD, these regulatory mechanisms may be compromised due to the persistent action of inflammatory mediators or exposure to environmental stressors, leading to a failure in the timely clearance of damaged mitochondria, which subsequently exacerbates the progression of COPD (Table 1)