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2.2.3 Activation of the MAPK signaling pathway MAPK are pivotal signaling mediators that respond to diverse stimuli, including physiological signals (e.g., hormones, cytokines, and growth factors) and stress-related cues (e.g., endogenous stress and environmental perturbations)

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has received consulting fees from Astellas Pharmaceuticals and Odyssey Therapeutics, and is an inventor on patents pertaining to Kras regulated metabolic pathways, redox control pathways in cancer, and targeting the GOT1-pathway as a therapeutic approach