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Biophys Rev 6(1):4761

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Combination of alpha lipoic acid and gabapentin, its efficacy in the treatment of burning mouth syndrome: a randomized, double-blind, placebo controlled trial

This is due to the fact that H 2 O 2 can quickly and readily diffuse through cell membranes, primarily through aquaporins (AQPs) 29,30 , as well as between neighbouring cells through gap junctions hemichannels composed of connexins which facilitate the transfer of molecules 13 kDa large such as ROS between cells to propagate oxidative signals 31