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Trends Food Sci Tech
A deeper understanding of nutrient distribution, metabolic rewiring, and the interrelation of cellular metabolism with signal transduction, gene expression, and epigenetic remodeling will aid the development of novel metabolic strategies to enhance the effectiveness of cancer immunotherapy
All rapidly dividing cells require nucleic acids at an increased rate, and some cancer cells appear to rely heavily on the TPP-dependent enzyme, transketolase, to provide the ribose-5-phosphate necessary for nucleic acid synthesis
Sexton URL: This study utilized cryogenic electron microscopy (cryo-EM) to elucidate the structural basis of cagrilintides interaction with amylin receptors (AMY1R, AMY2R, AMY3R) and the calcitonin receptor (CTR)
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