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88,89,90,91 Others have also studied whether controlled colonization with specific consortia of bacteria can reduce circulating IgE in GF mice

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doi: 10.2174/0929867322666151029104311 102 DrseSBrandtU

7 Conclusion and perspectives 7.1 Summary of key mechanisms The molecular mechanisms of macrophage polarization involve dynamic interactions among signaling networks, metabolic reprogramming, and epigenetic modifications, centered on the precise regulation of the balance between pro-inflammatory M1 and anti-inflammatory reparative M2 phenotypes