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7.2.2 Antioxidant therapy Oxidative stress, which arises from an imbalance between reactive oxygen species (ROS) production and the antioxidant defense mechanisms, is a key contributor to BBB dysfunction and neuroinflammation following intestinal I/R injury (Song et al., 2020)

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doi: 10.1111/jdi.12232 58 GeoffroyKTroncyLWiernspergerNLagardeMEl BawabS

STAT3 is a crucial factor in maintaining cell proliferation and survival, and can be activated by various cytokines to mediate immune and inflammatory responses (Figure 10)