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Acknowledgements This work was supported by the National Research Foundation of Korea (NRF) (grant number RS-2024-0034616660282063490101) and the Korea Evaluation Institute of Industrial Technology (KEIT) (grant number K-G012002335501)

Other symptoms include itching and bleeding There are three types of hemorrhoids External hemorrhoids are distal to the dentate line Internal hemorrhoids are proximal to the dentate line Mixed hemorrhoids are located both proximal and distal to the dentate line Internal hemorrhoids (above the dentate line): no pain, but bright red blood per rectum Internal hemorrhoids typically manifest with bleeding after defecation

(Lond) 14, 78, Review