A study showed that probiotic-fermented Pueraria lobata (Willd.) Ohwi significantly reduced the abundance of Bacteroidetes and Akkermansia muciniphila while increasing the abundance of Firmicutes and Lactobacillus , which modulated aberrant gut microbiota composition and activated nuclear transcription factor (erythroid-derived 2)-like 2 (Nrf2)-mediated signals, thereby improving lipid accumulation and inflammation and exerting antioxidant effects and ultimately preventing ALD ( in vivo and in vitro , which is inseparable from its impact on the gut microbiota ( Table 1 Research overview of TCMs and NPs targeting gut microbiota for liver disease therapy
Glucose transporter GLUT1 and glutamine transporter ASCT2 are upregulated in HCC, and the high expression of GLUT1 and ASCT2 indicates poor OS and recurrence-free survival (RFS) (Sun et al., 2016)
Hyperprolactinemia classically presents with galactorrhea, amenorrhea, and suppression of the hypothalamic-pituitary-gonadal axis due to inhibition of pulsatile GnRH release
Parades-Aguilar J, Reyes-Martnez V, Bustamante G, Almendriz-Tapia FJ, Martnez-Meza G, Vlchez-Vargas R, Link A, Certucha-Barragn MT, Caldern K (2021) Removal of Ni (II) from wastewater using a zeolite-packed anaerobic bioreactor: bacterial diversity and community structure shifts