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They are polarized tissues due to the differential expression of ion channels, pumps and transporters in the apical and the basolateral sides: (a) epithelial sodium channels (ENaC), Ca 2+ activated chloride channels and the cystic fibrosis transmembrane conductance regulator (CFTR) are present in the apical plasma membrane and (b) the Na + -K + -ATPase ion pump and the Na + -K + -2Cl cotransporter in the basolateral side

Whilst the UK Reference Nutrient Intake is 1.5 micrograms daily, prenatal vitamins typically contain higher amounts to ensure optimal maternal stores

Cell death was further assessed by counting nuclei and Propidium Iodide (PI) staining ( Figures 1D, E )

2016 Oct 4;316(13):1392-401