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Cognitive Function Cognitive function deteriorates with age and one of the key pathological events that precedes its development is reduced cerebral blood flow [89,90,91]

This facilitates the development and support of the cardiovascular system, the hepatic system, and the endocrine system

Indeed, an increased abundance of Akkermansia in PD individuals is correlated with an increased presence of co-occurring opportunistic pathogens (Wallen et al., 2020), thereby supporting the notion that higher levels of typically less common microbial species represent a risk factor in modifying PD pathophysiology (Wallen et al., 2020)

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