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Yang F, Tang X, Riquelme E, Behrens C, Nilsson MB, Giri U, Varella-Garcia M, Byers LA, Lin HY, Wang J, Raso MG, Girard L, Coombes K, Lee JJ, Herbst RS, Minna JD, Heymach JV , Wistuba II

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These molecular dynamics simulations mechanistically validate RAGE as a high-confidence target of AB4, consistent with the prioritization from network pharmacology