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Cysteine 10 is critical for the activity of Ochrobactrum anthropi glutathione transferase and its mutation to alanine causes the preferential binding of glutathione to the H-site

guideline failed to consider side effects and risks in recommendation formulation and was not externally reviewed

This one target, multiple effects or multiple targets synergistically characteristic enables them to simultaneously disrupt the mutually reinforcing relationships among oxidative stress, neuroinflammation, and protein toxicity

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