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It was estimated that OSA may affect approximately 1 billion of the worlds adult population (7.3 billion) and is even continuing to rising (104, 105)

Notably, ACSL4-driven lipid peroxidation is significantly potentiated under GPX4 deficiency (Wang R

Interestingly, some drugs based on the study of the regulatory mechanisms of ferroptosis in ovarian diseases, such as cryptotanshinone, N-acetylcysteine, rutin etc., has significantly improved ovarian function