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In addition, mitochondria lack more advanced repair pathways, such as nucleotide excision repair and homologous recombination, which makes mtDNA particularly susceptible to the accumulation of mutations [35], which leads to a higher rate of damaged mtDNA in mitochondria and further aggravates oocyte damage

ES2 is a senolytic peptide that targets FOXO4 CR3 but exhibits relatively poorer selectivity for senescent cells compared to FOXO4-DRI 25 (Table S1)

Polygenic Pharmacogenomic markers as predictors of toxicity phenotypes in the treatment of acute lymphoblastic leukemia: A Single-Center study

[] The interplay between mtMOF and the deacetylase SIRT3 dynamically regulates mitochondrial protein acetylation levels