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With further research, it is expected to transform from a research tool into a clinical drug, filling the niche in targeted metabolic therapy, especially in the combined intervention of obesity and type 2 diabetes, where it holds unique application potential

Even with total serum B12 concentrations considered to be within the normal range, neurological or in some cases hematological symptoms related to B12 deficiency have been reported

GLP-1-oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand obese (NZO) mice

Compared to participants without ASR, those with mild (OR 1.15, 95% CI 1.03-1.28), moderate or significant (OR 1.57, 95% CI 1.32-1.85) ASR had increased risks of poor functional recovery after adjustment for confounders