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These neurotransmitters do not only enhance cognitive function, but they also boost mood and overall mental health

The hypothesis of post-receptor alterations involved in resistance to SS analogs is supported by the dissociation between the antisecretory and antiproliferative effects of SS analogs observed in vivo in some acromegalic patients and in in vitro experiments in tumoral somatotroph cells where SS analogs exert antiproliferative effects without inhibition of GH secretion ( oA , independently of cAMP reduction, suggesting a dissociation between these pathways ( Few data are available about a possible role of G proteins alterations in pituitary tumor resistance to pharmacologic treatment with DA or SS analogs

Iron is considerably more toxic to cells expressing CYP2E1 than to cells not expressing this enzyme, and it is suspected that low concentrations of iron may act as a protective factor for CYP2E1 -induced injury

Perol S, Hugon-Rodin J, Plu-Bureau G