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doi: 10.1080/09513590.2017.1290071 114 WangZZhaiDZhangDBaiLYaoRYuJet al

[105], and GPx4 is the only known enzyme able to reduce lipid peroxides bound to cell membranes [106, 107]

As will be discussed, these genes were shown in literature to encode molecular programs that confer a competitive advantage to GBM in contexts such as chemotherapy and radiotherapy