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Therefore, it is essential to consult with a dermatologist before preparing for skin whitening treatment

Importantly, functional B12 deficiency can sometimes coexist with high total B12 levels, especially in kidney disease, and may require additional testing with methylmalonic acid (MMA) or holotranscobalamin if deficiency is suspected clinically

doi: 10.1016/0039-128x(94)90006-x 74 RyanR

Overall, the protein abundance log 2 ratios displayed a moderate correlation between S/P and S/Q ( R 2 =0.574), with 428 proteins (14.5%) significantly upregulated (log 2 S/P, S/Q1.5) and 475 (16.2%) downregulated (log 2 S/P, S/Q1.5)