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Quantitative dynamics of intracellular NMN by genetically encoded biosensor

For more than two decades, researchers pursued the goal of delivering GLP-1 receptor activation through an oral tablet, a pursuit complicated by the fundamental biochemistry of peptide drugs: their vulnerability to acid hydrolysis in the stomach, enzymatic degradation in the gastrointestinal tract, and poor absorption across the intestinal epithelium

Additionally, treated wounds demonstrated increased collagen deposition and angiogenesis (2)